Efficacy and safety of entacapone in levodopa/carbidopa versus levodopa/benserazide treated Parkinson’s disease patients with wearing-off
نویسندگان
چکیده
منابع مشابه
Entacapone Reduces Cortical Activation in Parkinson's Disease with Wearing-Off: A f-MRI Study
BACKGROUND AND PURPOSE Wearing-off is one of the most frequent problems encountered by levodopa-treated patients. Entacapone, a peripheral inhibitor of catechol-O-methyltransferase (COMT), reduces this motor complication by prolonging the effect of levodopa. We sought to understand the impact of COMT-inhibition on movement execution in PD patients with wearing-off by comparing functional magnet...
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ژورنال
عنوان ژورنال: Journal of Neural Transmission
سال: 2015
ISSN: 0300-9564,1435-1463
DOI: 10.1007/s00702-015-1449-6